Exercise Does Not Have The Same Effects On Everyone

A new study suggests that exercise might not exert the same effects on everyone. The paper, entitled “Effects of Exercise Training on Cardiorespiratory Fitness and Biomarkers of Cardiometabolic Health: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials” has been published in the Journal of the American Heart Association.

exercise

The researchers of the new paper found that the benefits of working out differ from person to person after they analysed the results of 160 clinical trials involving 7,500 participants; they evaluated the benefits of exercise that were found in all the studies.

For instance, some of the advantages are observed to be more pronounced in categories like males, those under 50, and people with type 2 diabetes as opposed to their opposite.

“Our meta-analysis is one of the first studies to systematically and
comprehensively evaluate the effectiveness of exercise interventions in affecting various cardiometabolic outcomes,” says lead author Xiaochen Lin, a doctoral student in the Brown University School of Public Health.

“Because the exact mechanisms linking exercise to intermediate health outcomes are not clear, we also wanted to examine the effects of exercise on intermediate biomarkers that may potentially mediate the cardioprotective effects of exercise.”

The researchers believe that the differences spotted might be important for doctors and patients to take account of before deciding which exercise plan to adhere to.

“Based on our findings, exercise interventions are not universally effective across different intermediate outcomes and subgroups of participants,” says corresponding author Simin Liu, professor of epidemiology and of medicine.

“Even though exercise may benefit most people under most circumstances, it does not mean that the same exercise program or therapy should be prescribed to everyone.”

One of the findings that stand out the most involves the significant effect of exercise on lowering insulin resistance and inflammation. Therefore, this data might be put into use to determine the right exercise plans for diabetics. Individualistic plans might be the preferred option.

“Besides exercise there are many modifiable lifestyle factors that could be the potential target of interventions for cardiometabolic health,” he says.

“If a subgroup of people cannot benefit from exercise, other alternatives should be considered. That’s one of the most important implications of evaluating the heterogeneity of exercise interventions.”

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